Magainin 1

CAS No. 108433-99-4

Magainin 1 ( )

Catalog No. M30461 CAS No. 108433-99-4

Magainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Magainin 1
  • Note
    Research use only, not for human use.
  • Brief Description
    Magainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis.
  • Description
    Magainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. (In Vitro):Magainin 1 interacts with acidic lipids through electrostatic interactions followed by hydrophobic interactions to form an amphiphilic helix, inducing the leakage. Magainin 1 induces the leakage of calcein specifically out of negatively-charged vesicles. The peptide binds to bovine brain phosphatidylserine sonicated vesicles according to the Langmuir isotherm with a binding constant of 3.8×105 M-1 and a binding-site number of 0.10 per lipid molecule.
  • Synonyms
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    108433-99-4
  • Formula Weight
    2409.9
  • Molecular Formula
    C112H177N29O28S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Duclohier H, et al. Antimicrobial peptide magainin I from Xenopus skin forms anion-permeable channels in planar lipid bilayers. Biophys J. 1989 Nov;56(5):1017-21.
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