Magainin 1 ( )

Catalog No. M30461 CAS No. 108433-99-4

Magainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Magainin 1
Note

Research use only, not for human use.
Brief Description

Magainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis.
Description

Magainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. (In Vitro):Magainin 1 interacts with acidic lipids through electrostatic interactions followed by hydrophobic interactions to form an amphiphilic helix, inducing the leakage. Magainin 1 induces the leakage of calcein specifically out of negatively-charged vesicles. The peptide binds to bovine brain phosphatidylserine sonicated vesicles according to the Langmuir isotherm with a binding constant of 3.8×105 M-1 and a binding-site number of 0.10 per lipid molecule.
Synonyms
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

108433-99-4
Formula Weight

2409.9
Molecular Formula

C112H177N29O28S
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

Duclohier H, et al. Antimicrobial peptide magainin I from Xenopus skin forms anion-permeable channels in planar lipid bilayers. Biophys J. 1989 Nov;56(5):1017-21.

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